{"n1":3252,"n2":3253,"e1":278,"p1":8.54859,"e2":308,"p2":9.46818,"hr":1.11,"low":0.95,"high":1.31,"intchi":0.382,"level":"No","subgroup":"Qual. diag.: Prior MI"} {"n1":4656,"n2":4667,"e1":493,"p1":10.58849,"e2":502,"p2":10.75637,"hr":1.02,"low":0.9,"high":1.15,"intchi":0.382,"level":"Yes","subgroup":"Qual. diag.: Prior MI"} {"n1":2002,"n2":1963,"e1":240,"p1":11.98801,"e2":232,"p2":11.81864,"hr":0.99,"low":0.82,"high":1.18,"intchi":0.393,"level":"No","subgroup":"Qual. diag.: Prior Coronary Revas."} {"n1":5906,"n2":5957,"e1":531,"p1":8.99086,"e2":578,"p2":9.70287,"hr":1.08,"low":0.96,"high":1.22,"intchi":0.393,"level":"Yes","subgroup":"Qual. diag.: Prior Coronary Revas."} {"n1":6706,"n2":6732,"e1":625,"p1":9.32001,"e2":663,"p2":9.84848,"hr":1.06,"low":0.95,"high":1.19,"intchi":0.668,"level":"No","subgroup":"Qual. diag.: Multivessel CHD"} {"n1":1202,"n2":1188,"e1":146,"p1":12.14642,"e2":147,"p2":12.37374,"hr":1.01,"low":0.8,"high":1.26,"intchi":0.668,"level":"Yes","subgroup":"Qual. diag.: Multivessel CHD"} {"n1":1914,"n2":1906,"e1":178,"p1":9.2999,"e2":185,"p2":9.70619,"hr":1.05,"low":0.85,"high":1.29,"intchi":0.972,"level":"Recent","subgroup":"Time from CHD event to randomization"} {"n1":5972,"n2":5999,"e1":592,"p1":9.91293,"e2":624,"p2":10.40173,"hr":1.05,"low":0.94,"high":1.18,"intchi":0.972,"level":"Remote","subgroup":"Time from CHD event to randomization"} {"n1":2140,"n2":2131,"e1":200,"p1":9.34579,"e2":169,"p2":7.93055,"hr":0.84,"low":0.69,"high":1.03,"intchi":0.014,"level":"No","subgroup":"CV risk factor: Age>=60 years"} {"n1":5768,"n2":5789,"e1":571,"p1":9.89945,"e2":641,"p2":11.07272,"hr":1.13,"low":1.01,"high":1.26,"intchi":0.014,"level":"Yes","subgroup":"CV risk factor: Age>=60 years"} {"n1":5279,"n2":5198,"e1":441,"p1":8.35385,"e2":468,"p2":9.00346,"hr":1.08,"low":0.95,"high":1.23,"intchi":0.522,"level":"No","subgroup":"CV risk factor: Diabetes req. pharm."} {"n1":2629,"n2":2722,"e1":330,"p1":12.5523,"e2":342,"p2":12.56429,"hr":1.01,"low":0.87,"high":1.18,"intchi":0.522,"level":"Yes","subgroup":"CV risk factor: Diabetes req. pharm."} {"n1":5173,"n2":5218,"e1":481,"p1":9.29828,"e2":503,"p2":9.63971,"hr":1.04,"low":0.91,"high":1.17,"intchi":0.664,"level":"No","subgroup":"CV risk factor: HDL-C <40 mg/dL"} {"n1":2734,"n2":2698,"e1":289,"p1":10.57059,"e2":305,"p2":11.30467,"hr":1.08,"low":0.92,"high":1.27,"intchi":0.664,"level":"Yes","subgroup":"CV risk factor: HDL-C <40 mg/dL"} {"n1":6239,"n2":6286,"e1":601,"p1":9.63295,"e2":637,"p2":10.13363,"hr":1.06,"low":0.95,"high":1.18,"intchi":0.708,"level":"No","subgroup":"CV risk factor: Current or previous smoker"} {"n1":1635,"n2":1593,"e1":166,"p1":10.15291,"e2":165,"p2":10.35782,"hr":1.01,"low":0.82,"high":1.25,"intchi":0.708,"level":"Yes","subgroup":"CV risk factor: Current or previous smoker"} {"n1":5558,"n2":5486,"e1":455,"p1":8.1864,"e2":440,"p2":8.02042,"hr":0.98,"low":0.86,"high":1.12,"intchi":0.114,"level":"No","subgroup":"CV risk factor: Sig. renal dysfunction"} {"n1":2350,"n2":2434,"e1":316,"p1":13.44681,"e2":370,"p2":15.20131,"hr":1.15,"low":0.99,"high":1.33,"intchi":0.114,"level":"Yes","subgroup":"CV risk factor: Sig. renal dysfunction"} {"n1":6706,"n2":6750,"e1":588,"p1":8.76827,"e2":616,"p2":9.12593,"hr":1.04,"low":0.93,"high":1.17,"intchi":0.634,"level":"No","subgroup":"CV risk factor: Polyvascular disease"} {"n1":1202,"n2":1170,"e1":183,"p1":15.22463,"e2":194,"p2":16.5812,"hr":1.1,"low":0.9,"high":1.35,"intchi":0.634,"level":"Yes","subgroup":"CV risk factor: Polyvascular disease"} {"n1":2688,"n2":2686,"e1":168,"p1":6.25,"e2":171,"p2":6.36634,"hr":1.02,"low":0.82,"high":1.26,"intchi":0.377,"level":"1","subgroup":"No. CV risk factor"} {"n1":2800,"n2":2801,"e1":268,"p1":9.57143,"e2":263,"p2":9.3895,"hr":0.98,"low":0.83,"high":1.16,"intchi":0.377,"level":"2","subgroup":"No. CV risk factor"} {"n1":2397,"n2":2398,"e1":334,"p1":13.93408,"e2":375,"p2":15.63803,"hr":1.14,"low":0.99,"high":1.32,"intchi":0.377,"level":">=3","subgroup":"No. CV risk factor"} {"n1":736,"n2":765,"e1":93,"p1":12.63587,"e2":79,"p2":10.3268,"hr":0.81,"low":0.6,"high":1.1,"intchi":0.07,"level":"Hispanic or Latino","subgroup":"Ethnicity"} {"n1":7172,"n2":7155,"e1":678,"p1":9.45343,"e2":731,"p2":10.21663,"hr":1.09,"low":0.98,"high":1.21,"intchi":0.07,"level":"Not Hispanic or Latino","subgroup":"Ethnicity"} {"n1":6189,"n2":6217,"e1":626,"p1":10.11472,"e2":654,"p2":10.51954,"hr":1.04,"low":0.94,"high":1.16,"intchi":0.254,"level":"White","subgroup":"Race group"} {"n1":196,"n2":170,"e1":22,"p1":11.22449,"e2":28,"p2":16.47059,"hr":1.62,"low":0.93,"high":2.84,"intchi":0.254,"level":"Black","subgroup":"Race group"} {"n1":591,"n2":599,"e1":57,"p1":9.64467,"e2":63,"p2":10.51753,"hr":1.07,"low":0.75,"high":1.53,"intchi":0.254,"level":"Central/South/South East Asian","subgroup":"Race group"} {"n1":763,"n2":761,"e1":47,"p1":6.1599,"e2":54,"p2":7.09593,"hr":1.15,"low":0.78,"high":1.7,"intchi":0.254,"level":"East Asian/Japanese","subgroup":"Race group"} {"n1":169,"n2":173,"e1":19,"p1":11.2426,"e2":11,"p2":6.35838,"hr":0.56,"low":0.27,"high":1.18,"intchi":0.254,"level":"Other","subgroup":"Race group"} {"n1":104,"n2":110,"e1":12,"p1":11.53846,"e2":6,"p2":5.45455,"hr":0.45,"low":0.17,"high":1.19,"intchi":0.335,"level":"American Indian or Alaska Native","subgroup":"FDA race group"} {"n1":1354,"n2":1363,"e1":104,"p1":7.68095,"e2":117,"p2":8.58401,"hr":1.11,"low":0.85,"high":1.45,"intchi":0.335,"level":"Asian","subgroup":"FDA race group"} {"n1":196,"n2":170,"e1":22,"p1":11.22449,"e2":28,"p2":16.47059,"hr":1.62,"low":0.93,"high":2.84,"intchi":0.335,"level":"Black","subgroup":"FDA race group"} {"n1":5,"n2":10,"e1":1,"p1":20,"e2":1,"p2":10,"hr":0.53,"low":0.03,"high":8.43,"intchi":0.335,"level":"Native Hawaiian or Other Pacific Islander","subgroup":"FDA race group"} {"n1":6191,"n2":6219,"e1":626,"p1":10.11145,"e2":654,"p2":10.51616,"hr":1.04,"low":0.94,"high":1.16,"intchi":0.335,"level":"White","subgroup":"FDA race group"} {"n1":58,"n2":48,"e1":6,"p1":10.34483,"e2":4,"p2":8.33333,"hr":0.88,"low":0.25,"high":3.13,"intchi":0.335,"level":"Other Mixed Race","subgroup":"FDA race group"} {"n1":6191,"n2":6219,"e1":626,"p1":10.11145,"e2":654,"p2":10.51616,"hr":1.04,"low":0.94,"high":1.16,"intchi":0.735,"level":"White","subgroup":"Race group collapsed"} {"n1":1717,"n2":1701,"e1":145,"p1":8.44496,"e2":156,"p2":9.17108,"hr":1.09,"low":0.87,"high":1.37,"intchi":0.735,"level":"Non-white","subgroup":"Race group collapsed"} {"n1":2016,"n2":2007,"e1":201,"p1":9.97024,"e2":198,"p2":9.86547,"hr":1,"low":0.82,"high":1.21,"intchi":0.155,"level":"North America","subgroup":"Region"} {"n1":1768,"n2":1763,"e1":194,"p1":10.97285,"e2":179,"p2":10.15315,"hr":0.92,"low":0.75,"high":1.13,"intchi":0.155,"level":"Eastern Europe","subgroup":"Region"} {"n1":1979,"n2":2007,"e1":173,"p1":8.74179,"e2":221,"p2":11.01146,"hr":1.27,"low":1.04,"high":1.55,"intchi":0.155,"level":"Western Europe","subgroup":"Region"} {"n1":596,"n2":603,"e1":77,"p1":12.91946,"e2":71,"p2":11.77446,"hr":0.92,"low":0.66,"high":1.27,"intchi":0.155,"level":"South America","subgroup":"Region"} {"n1":1549,"n2":1540,"e1":126,"p1":8.13428,"e2":141,"p2":9.15584,"hr":1.13,"low":0.89,"high":1.43,"intchi":0.155,"level":"Asia/Pacific","subgroup":"Region"} {"n1":1553,"n2":1549,"e1":161,"p1":10.36703,"e2":160,"p2":10.32924,"hr":1.01,"low":0.81,"high":1.25,"intchi":0.652,"level":"US","subgroup":"United States Subgroup"} {"n1":6355,"n2":6371,"e1":610,"p1":9.59874,"e2":650,"p2":10.20248,"hr":1.07,"low":0.95,"high":1.19,"intchi":0.652,"level":"Non-US","subgroup":"United States Subgroup"} {"n1":6435,"n2":6426,"e1":637,"p1":9.89899,"e2":651,"p2":10.13072,"hr":1.03,"low":0.92,"high":1.14,"intchi":0.28,"level":"Male","subgroup":"Gender"} {"n1":1473,"n2":1494,"e1":134,"p1":9.09708,"e2":159,"p2":10.64257,"hr":1.18,"low":0.94,"high":1.48,"intchi":0.28,"level":"Female","subgroup":"Gender"} {"n1":4881,"n2":4811,"e1":403,"p1":8.2565,"e2":421,"p2":8.75078,"hr":1.06,"low":0.92,"high":1.21,"intchi":0.85,"level":"No","subgroup":"B/L diabetes status"} {"n1":3027,"n2":3109,"e1":368,"p1":12.15725,"e2":389,"p2":12.51206,"hr":1.04,"low":0.9,"high":1.2,"intchi":0.85,"level":"Yes","subgroup":"B/L diabetes status"} {"n1":3864,"n2":3837,"e1":331,"p1":8.56625,"e2":321,"p2":8.36591,"hr":0.97,"low":0.83,"high":1.13,"intchi":0.2,"level":"<65 years","subgroup":"Age at randomization"} {"n1":2972,"n2":2988,"e1":296,"p1":9.95962,"e2":310,"p2":10.37483,"hr":1.05,"low":0.9,"high":1.23,"intchi":0.2,"level":"65-74 years","subgroup":"Age at randomization"} {"n1":1072,"n2":1095,"e1":144,"p1":13.43284,"e2":179,"p2":16.34703,"hr":1.24,"low":1,"high":1.54,"intchi":0.2,"level":">=75 years","subgroup":"Age at randomization"} {"n1":3997,"n2":3958,"e1":362,"p1":9.05679,"e2":393,"p2":9.92926,"hr":1.1,"low":0.95,"high":1.27,"intchi":0.441,"level":"Target","subgroup":"B/L blood pressure"} {"n1":3906,"n2":3959,"e1":407,"p1":10.41987,"e2":417,"p2":10.53296,"hr":1.02,"low":0.89,"high":1.16,"intchi":0.441,"level":"High","subgroup":"B/L blood pressure"} {"n1":1065,"n2":1148,"e1":163,"p1":15.30516,"e2":193,"p2":16.81185,"hr":1.12,"low":0.91,"high":1.38,"intchi":0.465,"level":"<60 ml/min/1.73m2","subgroup":"B/L eGFR"} {"n1":6828,"n2":6760,"e1":608,"p1":8.90451,"e2":615,"p2":9.09763,"hr":1.02,"low":0.91,"high":1.14,"intchi":0.465,"level":">=60 ml/min/1.73m2","subgroup":"B/L eGFR"} {"n1":2720,"n2":2699,"e1":229,"p1":8.41912,"e2":251,"p2":9.29974,"hr":1.11,"low":0.93,"high":1.33,"intchi":0.081,"level":"<1.80 mmol/L","subgroup":"B/L LDL-C"} {"n1":3079,"n2":3131,"e1":268,"p1":8.70412,"e2":311,"p2":9.93293,"hr":1.15,"low":0.98,"high":1.36,"intchi":0.081,"level":">=1.80-<2.58 mmol/L","subgroup":"B/L LDL-C"} {"n1":2090,"n2":2078,"e1":274,"p1":13.11005,"e2":247,"p2":11.88643,"hr":0.9,"low":0.75,"high":1.06,"intchi":0.081,"level":">=2.58 mmol/L","subgroup":"B/L LDL-C"} {"n1":2400,"n2":2350,"e1":266,"p1":11.08333,"e2":277,"p2":11.78723,"hr":1.08,"low":0.91,"high":1.28,"intchi":0.924,"level":"<1.03 mmol/L","subgroup":"B/L HDL-C"} {"n1":4345,"n2":4424,"e1":397,"p1":9.13694,"e2":418,"p2":9.44846,"hr":1.03,"low":0.9,"high":1.19,"intchi":0.924,"level":">=1.03-<1.55 mmol/L","subgroup":"B/L HDL-C"} {"n1":1149,"n2":1136,"e1":108,"p1":9.39948,"e2":114,"p2":10.03521,"hr":1.07,"low":0.82,"high":1.39,"intchi":0.924,"level":">=1.55 mmol/L","subgroup":"B/L HDL-C"} {"n1":2544,"n2":2583,"e1":204,"p1":8.01887,"e2":225,"p2":8.7108,"hr":1.1,"low":0.91,"high":1.33,"intchi":0.173,"level":"First tertile","subgroup":"B/L XYX Test evel"} {"n1":2591,"n2":2544,"e1":210,"p1":8.10498,"e2":248,"p2":9.74843,"hr":1.21,"low":1.01,"high":1.45,"intchi":0.173,"level":"Second tertile","subgroup":"B/L XYX Test evel"} {"n1":2558,"n2":2559,"e1":326,"p1":12.74433,"e2":315,"p2":12.3095,"hr":0.96,"low":0.83,"high":1.13,"intchi":0.173,"level":"Third tertile","subgroup":"B/L XYX Test evel"} {"n1":2773,"n2":2729,"e1":208,"p1":7.5009,"e2":208,"p2":7.62184,"hr":1.02,"low":0.84,"high":1.23,"intchi":0.35,"level":"<1.0 mg/L","subgroup":"B/L hs C-reactive protein"} {"n1":2565,"n2":2656,"e1":265,"p1":10.33138,"e2":269,"p2":10.12801,"hr":0.98,"low":0.83,"high":1.16,"intchi":0.35,"level":"1.0-3.0 mg/L","subgroup":"B/L hs C-reactive protein"} {"n1":1851,"n2":1832,"e1":220,"p1":11.88547,"e2":251,"p2":13.70087,"hr":1.17,"low":0.97,"high":1.4,"intchi":0.35,"level":">3.0 mg/L","subgroup":"B/L hs C-reactive protein"} {"n1":5905,"n2":5831,"e1":598,"p1":10.12701,"e2":589,"p2":10.10118,"hr":1,"low":0.89,"high":1.12,"intchi":0.05,"level":"No","subgroup":"Family history of CHD"} {"n1":1986,"n2":2071,"e1":170,"p1":8.55992,"e2":218,"p2":10.52632,"hr":1.25,"low":1.03,"high":1.53,"intchi":0.05,"level":"Yes","subgroup":"Family history of CHD"} {"n1":1640,"n2":1664,"e1":152,"p1":9.26829,"e2":178,"p2":10.69712,"hr":1.14,"low":0.92,"high":1.41,"intchi":0.524,"level":"<25 kg/m2","subgroup":"Body mass index at baseline"} {"n1":3394,"n2":3358,"e1":332,"p1":9.78197,"e2":321,"p2":9.55926,"hr":0.98,"low":0.84,"high":1.15,"intchi":0.524,"level":"25-<30 kg/m2","subgroup":"Body mass index at baseline"} {"n1":2851,"n2":2878,"e1":286,"p1":10.03157,"e2":305,"p2":10.59764,"hr":1.07,"low":0.91,"high":1.25,"intchi":0.524,"level":">=30 kg/m2","subgroup":"Body mass index at baseline"} {"n1":959,"n2":1000,"e1":84,"p1":8.75912,"e2":99,"p2":9.9,"hr":1.12,"low":0.84,"high":1.5,"intchi":0.825,"level":"Level 1: Males: <=0.90, Females: <=0.83","subgroup":"Waist/hip ratio at baseline"} {"n1":1979,"n2":1926,"e1":165,"p1":8.33754,"e2":174,"p2":9.03427,"hr":1.08,"low":0.88,"high":1.34,"intchi":0.825,"level":"Level 2: Males: >0.90-<=0.95, Females: >0.83-<=0.9","subgroup":"Waist/hip ratio at baseline"} {"n1":4865,"n2":4897,"e1":512,"p1":10.52415,"e2":527,"p2":10.76169,"hr":1.03,"low":0.91,"high":1.16,"intchi":0.825,"level":"Level 3: Males: >0.95, Females: >0.90","subgroup":"Waist/hip ratio at baseline"} {"n1":609,"n2":595,"e1":67,"p1":11.00164,"e2":77,"p2":12.94118,"hr":1.21,"low":0.87,"high":1.67,"intchi":0.39,"level":"No","subgroup":"B/L aspirin use"} {"n1":7298,"n2":7325,"e1":704,"p1":9.64648,"e2":733,"p2":10.00683,"hr":1.04,"low":0.94,"high":1.15,"intchi":0.39,"level":"Yes","subgroup":"B/L aspirin use"} {"n1":212,"n2":217,"e1":20,"p1":9.43396,"e2":31,"p2":14.28571,"hr":1.55,"low":0.88,"high":2.71,"intchi":0.177,"level":"No","subgroup":"B/L statin use"} {"n1":7695,"n2":7703,"e1":751,"p1":9.75958,"e2":779,"p2":10.11294,"hr":1.04,"low":0.94,"high":1.15,"intchi":0.177,"level":"Yes","subgroup":"B/L statin use"} {"n1":1670,"n2":1649,"e1":137,"p1":8.20359,"e2":194,"p2":11.76471,"hr":1.46,"low":1.17,"high":1.81,"intchi":0.001,"level":"No","subgroup":"B/L beta-blocker use"} {"n1":6237,"n2":6271,"e1":634,"p1":10.16514,"e2":616,"p2":9.82299,"hr":0.97,"low":0.87,"high":1.08,"intchi":0.001,"level":"Yes","subgroup":"B/L beta-blocker use"} {"n1":5222,"n2":5202,"e1":493,"p1":9.44083,"e2":548,"p2":10.53441,"hr":1.13,"low":1,"high":1.27,"intchi":0.066,"level":"No","subgroup":"B/L P2Y12 inhibitor use"} {"n1":2685,"n2":2718,"e1":278,"p1":10.35382,"e2":262,"p2":9.63944,"hr":0.93,"low":0.78,"high":1.1,"intchi":0.066,"level":"Yes","subgroup":"B/L P2Y12 inhibitor use"} {"n1":1850,"n2":1776,"e1":164,"p1":8.86486,"e2":157,"p2":8.84009,"hr":1,"low":0.81,"high":1.25,"intchi":0.632,"level":"No","subgroup":"B/L ACE inhibitor/Angiotensin II receptor blocker use"} {"n1":6057,"n2":6144,"e1":607,"p1":10.02146,"e2":653,"p2":10.62826,"hr":1.06,"low":0.95,"high":1.19,"intchi":0.632,"level":"Yes","subgroup":"B/L ACE inhibitor/Angiotensin II receptor blocker use"} {"n1":2423,"n2":2464,"e1":229,"p1":9.45109,"e2":238,"p2":9.65909,"hr":1.03,"low":0.86,"high":1.23,"intchi":0.938,"level":"Never smoked","subgroup":"Smoking status"} {"n1":1447,"n2":1411,"e1":162,"p1":11.19558,"e2":167,"p2":11.83558,"hr":1.05,"low":0.85,"high":1.31,"intchi":0.938,"level":"Current smoker","subgroup":"Smoking status"} {"n1":4036,"n2":4045,"e1":380,"p1":9.41526,"e2":405,"p2":10.01236,"hr":1.07,"low":0.93,"high":1.23,"intchi":0.938,"level":"Former smoker","subgroup":"Smoking status"}